On World Cancer Day, a day dedicated to the global fight against cancer, we at Cellis are incredibly proud to mark this occasion with a major scientific milestone: our latest research has just been published in Nature Communications!
This paper represents 10 years of relentless research, bringing us closer to a future where macrophage-based therapies can revolutionize the treatment of solid tumors.
🔬 What’s the breakthrough?
Our study introduces the Macrophage-Drug Conjugate (MDC) platform, a novel approach harnessing macrophages to deliver anti-cancer drugs to tumors via the TRAIN mechanism (TRAnsfer of Iron-binding protein). By leveraging the natural biology of macrophages and their interaction with cancer cells, we demonstrate a powerful strategy for targeted therapy—one that is both effective and clinically viable.
👩🔬👨🔬 Meet the brilliant minds behind this work:
Bartłomiej Taciak, Maciej Białasek, Małgorzata Kubiak, Ilona Marszałek, Małgorzata Górczak, Olha Osadchuk, Daria Kurpiel, Damian Strzemecki, Karolina Barwik, Marcin Skórzyński, Julia Nowakowska, Waldemar Lipiński, Łukasz Kiraga, Jan Brancewicz, Robert Klopfleisch, Lukasz Krzeminski, Emilia Górka, Anna Smolarska, Irena Barbara Pruszyńska, Małgorzata Siemińska, Jakub Guzek, Jan Kutner, Marlena Kisiała, Krzysztof Woźniak, Giacomo Parisi, Roberta Piacentini, Luca Cassetta, Lesley M. Forrester, Lubomir Bodnar, Tobias Weiss, Alberto Boffi, Paulina Kucharzewska, Tomasz Rygiel & Magdalena Król.
Read the full paper here: https://www.nature.com/articles/s41467-025-56637-9
As we observe World Cancer Day, it’s immensely satisfying to contribute meaningful progress to the fight against cancer. Our work doesn’t stop here—this is just the beginning. Stay tuned!
